VERO Cell Catalogue Number: 605372

VERO Cells: A Cornerstone in Vaccine Development and Virology Research

VERO cells, derived from the kidney of an African green monkey in the 1960s by Japanese scientists at Chiba University, have become a vital tool in various biomedical research fields. These include vaccine development, viral infection studies, malaria research, tumor immunology, and immunotherapy.

Key Features and Applications
One defining characteristic of VERO cells is their rapid growth rate, with a population doubling time of approximately 24 hours. Their stability, combined with their ability to produce high viral titers, makes them an ideal platform for vaccine production. For instance, the VERO cell-derived vaccine for Japanese encephalitis is widely used and licensed globally.

VERO cells have been instrumental in developing vaccines for numerous infectious diseases, including:

Rubella virus
– Ross River virus
– Herpes simplex virus
– Measles virus
– Poliovirus
These cells are renowned for their ability to produce, grow, and maintain viruses under optimized culture conditions. They are crucial for generating viral vectors, which play a significant role in vaccine development, tissue engineering, and virus isolation.

Specialized VERO Cell Lines
Several VERO cell lines cater to diverse research and production requirements:

Vero 76 Cells: Known for their robust growth and high virus yield, they are a primary choice for vaccine production.
Vero E6 Cells: This subclone demonstrates enhanced sensitivity to specific viruses, such as the Ebola virus and SARS-CoV-2, making it invaluable for studying viral pathogenesis and screening antiviral drugs.

Broader Impact
The versatility and efficiency of VERO cells have made them an indispensable tool in virology research and vaccine production. Their role in combating infectious diseases and advancing antiviral therapies underscores their critical importance in global health initiatives. Whether for vaccine development, viral vector generation, or disease pathogenesis studies, VERO cells remain at the forefront of biomedical research and innovation.